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In some cases, multiple attempts will be made before sobriety takes hold. For example, someone who has a hard time sleeping might be prescribed a non-addictive sleep medication. Someone who experiences bone aches or muscle pains may be offered a pain reliever.

Opioid detox is a bit different from detox options frequently provided for other substances of abuse and addiction. There are medications that have been approved by the Food and Drug Administration solely to treat opioid addiction.